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MYP_150197
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Basic Information
Bombolitin-8 (Insects, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
19 amino acids
C97H176N26O23
Standard
Sequence
LKLKSILGKLGVILSHLNK
Physicochemical Analysis
2074.60 Da
10.48
3.84
3.58
0.2023
0.59
0.40
0.19
19.87
179.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
803.43
-4.25
28.0
28.0
76.0
146.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046247 VERIFIED: YES
Provenance & Taxonomy
Bombus lapidarius [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID: 16626777 PMID16626777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16626777/
RECORD: Rec_0078624 VERIFIED: NO
Provenance & Taxonomy
Bombus lapidarius [Animal]
MCD
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Toxin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID16626777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16626777/; https://www.uniprot.org/uniprotkb/P0CD69/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0218832 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0371422 VERIFIED: NO
Provenance & Taxonomy
Bombus lapidarius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Antimicrobial Antibacterial Antifungal