Peptide Database

Peptide NameSLAY-screened peptide P1287

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC105H159N21O28S2

DescriptionStandard

        PCLVYCTDLPAVNLPYISVF
    

Molecular Weight2227.64 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.06

Net Charge (pH 7.4) -1.15

Charge Density (pH 7.0) -0.0531

GRAVY Index1.11

Hydrophobic Moment 0.11

Boman Index0.46

Instability Index56.78

Aliphatic Index 126.50

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 745.96

LogP -3.06

H-bond Donors 27.0

H-bond Acceptors 29.0

Rotatable Bonds 62.0

Heavy Atoms 156.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409292 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/