Peptide Database

Peptide NameBeta-defensin 40

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC390H606N108O93S10

DescriptionStandard

        MKISCFLLMIFFLSCFQINPVAVLDTIKCLQGNNNCHIQKCPWFLLQVSTCYKGKGRCCQKRRWFARSHVYHV
    

Molecular Weight8616.30 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)8.68

Net Charge (pH 7.4) 8.18

Charge Density (pH 7.0) 0.1188

GRAVY Index0.20

Hydrophobic Moment 0.40

Boman Index0.08

Instability Index60.68

Aliphatic Index 86.71

Aromaticity 0.1370

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3249.23

LogP -24.41

H-bond Donors 121.0

H-bond Acceptors 115.0

Rotatable Bonds 283.0

Heavy Atoms 601.0

Ring Count 17.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0135890 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0295752 VERIFIED: NO