Peptide Database

Peptide NameIndolicidin [W4H,W6H,W8H,W9H,W11H]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC75H116N30O14

DescriptionStandard

        ILPHKHPHHPHRR
    

Molecular Weight1661.92 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.74

Charge Density (pH 7.0) 0.2458

GRAVY Index-1.95

Hydrophobic Moment 0.45

Boman Index-0.44

Instability Index96.71

Aliphatic Index 60.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 679.37

LogP -4.69

H-bond Donors 23.0

H-bond Acceptors 22.0

Rotatable Bonds 48.0

Heavy Atoms 119.0

Ring Count 8.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171028 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus ATCC 9341

Activity100 μM

MethodMIC

RECORD: Rec_0200000 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity100 % hemolysis at >1000 μM

MethodHemolysis