Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length482 amino acids

Chemical FormulaC2501H3934N656O666S18

DescriptionStandard

        MAWGPDNVRRWSTLALLAIMGTALTAAINPGFVAVITQMGLDFACREAVAVLQKELKTIKIPNFSGVFKMKHLGKGYYDFHSMTVDGFHIPNPHVNLLPTDGLQLFIRDAGIKISGRWKSKKNFFKASGKFGLSIQRVSISSDLKITRNPSGHLNVKCSFCSSHIGRVRVQISGSMLGWLIQLFHKNIETSLRNIIYDKICRIVINSVSTQLQPYVQTLPVIARVDDITAIDYSLLVLTATTEFLEGKLKGEFFWRERRSILPFIPPTMDFFPDKDHMVYLVISDYFFNTAGFAYHESGNLKITLRNEMLPEDSKFHLNTELLGNFLPKVALMFPSTEIQLLISSSTPPRLLIQPSGLLLHPAMETQAFVVLPNSSLVPLFLLLVVSWNTNASLEVDVEANRLVGEMKLEKRWVPIHPWVFRRVELLQAVLNYLMPTIVLPKINERLHRGFPLPLPAGAQLNNLMFQAYQNFLVLGADVHRS
    

Molecular Weight54425.15 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)12.72

Net Charge (pH 7.4) 11.64

Charge Density (pH 7.0) 0.0264

GRAVY Index0.15

Hydrophobic Moment 0.72

Boman Index0.14

Instability Index37.01

Aliphatic Index 106.56

Aromaticity 0.0996

Extinction Coeff. Reduced 58900.00

Extinction Coeff. Oxidized 59150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300362 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus (Chinese hamster) [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria