Peptide Database

Peptide NameEsculentin-2N protein (Fragment)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC299H502N84O101S4

DescriptionStandard

        GTISLSLCKEERDADEDDGGEMKEELVKRGFLSLLSNAAKFLGKTLLKNVGKAGLETAACKATNQC
    

Molecular Weight7017.95 Da

Isoelectric Point (pI)5.34

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.53

Charge Density (pH 7.0) -0.0190

GRAVY Index-0.35

Hydrophobic Moment 0.62

Boman Index-0.06

Instability Index20.97

Aliphatic Index 84.39

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3031.28

LogP -34.79

H-bond Donors 107.0

H-bond Acceptors 104.0

Rotatable Bonds 251.0

Heavy Atoms 488.0

Ring Count 2.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106166 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

FamilyEsculentin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0395183 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal