Peptide Database

Peptide NameDermaseptin B2 (1-23)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC104H178N30O29

DescriptionStandard

        GLWSKIKEVGKEAAKAAAKAAGK
    

Molecular Weight2312.71 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.54

Charge Density (pH 7.0) 0.1635

GRAVY Index-0.36

Hydrophobic Moment 0.68

Boman Index-0.02

Instability Index1.40

Aliphatic Index 76.96

Aromaticity 0.0435

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 970.26

LogP -8.93

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 83.0

Heavy Atoms 163.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232987 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetRat erythrocytes (0% Hemolysis at 50 microM, Chinese hamster ovary cells CHO (0% Cytotoxicity at 50 microM

Activity50 μM

MethodHemolysis

RECORD: Rec_0297510 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa

Activity100 μM

MethodMIC

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