Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC901H1447N265O276S15

DescriptionStandard

        MSLKSTATKAGGITCSVMGIIALVVSSTSTHVRTNQEGLEIIGNAEGCMRNPYVCPTGYLTVGIGSRIYENEPAVRRPGLTDQEIADRWVKNIQEAEKCVNDWFHGKDMNDNQFSAMTSMVFNHGCTKLRKNKDGSPTKIYTAARYQNWTEMCNRITDWDMGGKYRGLTIRKQKEKALCLKPVPSSR
    

Molecular Weight20888.71 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)7.71

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.0412

GRAVY Index-0.53

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index34.70

Aliphatic Index 66.74

Aromaticity 0.0695

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8805.51

LogP -110.83

H-bond Donors 315.0

H-bond Acceptors 302.0

Rotatable Bonds 702.0

Heavy Atoms 1457.0

Ring Count 27.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383372 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoM_fHy-Eco03 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic