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MYP_150084
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Basic Information
Casein beta [060-063]
Anticancer
Anticancer ▸ Anti-breast cancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
4 amino acids
C28H34N4O6
Standard
Sequence
YPFP
Physicochemical Analysis
522.59 Da
5.52
-0.24
-0.45
-0.0602
-0.42
0.23
0.42
134.65
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
153.27
1.06
4.0
6.0
9.0
38.0
4.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058590 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Myenteric plexus of guinea pig ileum longitudianal muscle
7.5 μM
IC50
RECORD: Rec_0171971 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0298558 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Opioid receptor ligand
PaperSynthesis and biological evaluation of novel peripherally active morphiceptin analogs | Gach, K. et al. | DOI: 10.1016/j.peptides.2010.04.018 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0305967 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperBrantl V., Teschemacher H., Henschen A., Lottspeich F.. Novel opioid peptides derived from casein (beta-casomorphins). I. Isolation from bovine casein peptone. Hoppe-Seylers Z. Physiol. Chem., 360, 1211-1216, 1979.
RECORD: Rec_0326867 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
Myenteric plexus of guinea pig ileum longitudianal muscle
0.13 μM
IC50
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