Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length459 amino acids

Chemical FormulaC2315H3658N630O653S11

DescriptionStandard

        TNPGFMVRITQAGLDYAHQHGIAILEKELAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFHLPYSRITPISNEGLQVSISNAFAELDGDWRVKFLFVRDHGSFNLKVENVYIKITLRLGSDTTGKPTTSTSDCSARISKVRVLFSGRFGWLYNLFHSAIESRLRKSLEQKICDNVVKSVHSDLQTYLRTLPVTARIDDKTGIDYSLVAPPRATDQSLDAALKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKDVGFKLDTSVFSAFIPQLEEMYPNMSMKFRLTAPTAPFLTIGPGGILFQPIVDAQAYAILPNSSLVPLFLLSLVRNVSAVINVRSGRIVGSLDVGRYRGEQPLTGQGVVGDVSVRMMQSLMNVLTSSTLLPRLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVHFQPR
    

Molecular Weight51116.35 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)8.47

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.0184

GRAVY Index0.03

Hydrophobic Moment 0.66

Boman Index0.08

Instability Index31.79

Aliphatic Index 100.65

Aromaticity 0.0937

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0274301 VERIFIED: NO

Provenance & Taxonomy

OrganismAlaudala cheleensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria