Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 4

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC450H736N138O148S7

DescriptionStandard

        MKTLALLAALLLLALQVQTQSLEETADQVPAQDQPGAEAQDITISFAGDERSAREASKSLTGTASCTCRRAWICKWGERHSGNCIDQEGSAYRLCCRR
    

Molecular Weight10671.95 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0148

GRAVY Index-0.32

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index47.13

Aliphatic Index 79.90

Aromaticity 0.0408

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4661.05

LogP -57.03

H-bond Donors 170.0

H-bond Acceptors 155.0

Rotatable Bonds 360.0

Heavy Atoms 743.0

Ring Count 9.0

Amide Bonds 106.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0314730 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal