Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC126H206N32O39S6

DescriptionStandard

        PCGESCVYIPCISSLLGCSCKSKVCYKN
    

Molecular Weight2985.56 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.74

Charge Density (pH 7.0) 0.0677

GRAVY Index0.38

Hydrophobic Moment 0.34

Boman Index0.13

Instability Index29.16

Aliphatic Index 76.43

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1126.30

LogP -13.26

H-bond Donors 46.0

H-bond Acceptors 47.0

Rotatable Bonds 96.0

Heavy Atoms 203.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245446 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)