Peptide Database

Peptide NameSLAY-screened peptide P4708

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC91H133N21O25S3

DescriptionStandard

        SGAALFYMPCYAPVSTHMA
    

Molecular Weight2017.35 Da

Isoelectric Point (pI)6.45

Net Charge (pH 7.0)-0.46

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0245

GRAVY Index0.66

Hydrophobic Moment 0.13

Boman Index0.41

Instability Index103.68

Aliphatic Index 56.84

Aromaticity 0.1579

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 699.37

LogP -5.54

H-bond Donors 25.0

H-bond Acceptors 29.0

Rotatable Bonds 56.0

Heavy Atoms 140.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211802 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/