Peptide Database

Peptide NameRilonacept

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC347H515N93O103S3

DescriptionStandard

        SERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKFNYSTAHSAGLTLIWYWTRQDRDLEEPIN
    

Molecular Weight7733.56 Da

Isoelectric Point (pI)4.74

Net Charge (pH 7.0)-5.37

Net Charge (pH 7.4) -5.72

Charge Density (pH 7.0) -0.0838

GRAVY Index-0.68

Hydrophobic Moment 0.64

Boman Index-0.09

Instability Index26.78

Aliphatic Index 70.16

Aromaticity 0.1406

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3181.64

LogP -25.86

H-bond Donors 112.0

H-bond Acceptors 103.0

Rotatable Bonds 250.0

Heavy Atoms 546.0

Ring Count 17.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354978 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyFusion protein

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory IL-1 trap

Half-Life8.6 d