Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC241H384N68O77S6

DescriptionStandard

        MEEKMCLGALNALQEFQIEELDNLLGGRGHGVNTISAECRWNSLQAIFTCC
    

Molecular Weight5658.43 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-4.44

Net Charge (pH 7.4) -4.77

Charge Density (pH 7.0) -0.0870

GRAVY Index-0.00

Hydrophobic Moment 0.42

Boman Index0.09

Instability Index75.59

Aliphatic Index 90.00

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2356.26

LogP -24.24

H-bond Donors 83.0

H-bond Acceptors 80.0

Rotatable Bonds 193.0

Heavy Atoms 392.0

Ring Count 5.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282273 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus pyogenes [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence