Peptide Database

Peptide NameCecropin-B2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC286H490N82O72S

DescriptionStandard

        MNFNKLFLIVILAALLLLGQTEAGRSKKLGKKIEKAGKRVFNAAQKGLPVAAGVQALGR
    

Molecular Weight6261.52 Da

Isoelectric Point (pI)11.24

Net Charge (pH 7.0)8.50

Net Charge (pH 7.4) 8.27

Charge Density (pH 7.0) 0.1440

GRAVY Index0.27

Hydrophobic Moment 0.84

Boman Index0.10

Instability Index34.70

Aliphatic Index 120.85

Aromaticity 0.0508

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2509.79

LogP -20.33

H-bond Donors 86.0

H-bond Acceptors 82.0

Rotatable Bonds 222.0

Heavy Atoms 441.0

Ring Count 4.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306640 VERIFIED: NO

Provenance & Taxonomy

OrganismCulex pipiens pipiens [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence