Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length296 amino acids

Chemical FormulaC1458H2258N404O456S5

DescriptionStandard

        MRFRIEEDPESGELVSRSYEVGGKSGLDRVRVRFAKQLNKETWGFEDPSIKGTFVWSRSAGQGKFEWGSSQTTVHDGGAGGSTTPPTPIPEPRSVWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFQKASVRDLEVDYYGNFEGRSRQGLYEVDHIPSKEAVRIYLKGTYPNLKDDIIEQMTDRVAAVAIPIEVHRQCSETYGGKNNSKFRTQDGGLVTQKVLDASNLEAAVDANWDVNAECLRNEYGVSDEKIEEIRAKLHELNRKAGLY
    

Molecular Weight32902.28 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-12.10

Net Charge (pH 7.4) -12.64

Charge Density (pH 7.0) -0.0409

GRAVY Index-0.61

Hydrophobic Moment 0.64

Boman Index-0.06

Instability Index45.90

Aliphatic Index 73.41

Aromaticity 0.0878

Extinction Coeff. Reduced 43890.00

Extinction Coeff. Oxidized 44015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0308717 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)