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MYP_149823
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Basic Information
U3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KXWKLXK
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0189991 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
①The X (position: 2 and 6) in sequence are (S)-α-methyl, α-pentenylglycine. Note: the Experimental section presenst that X is (S)-α-methyl, α-pentenylglycine, while the Results section presents that X is pentenylalanine. We incline to the former representation according to previous papers published by the research group which the author belonged
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium ATCC 14028
100 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?id=DRAMP21608
RECORD: Rec_0190548 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,6
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
25 μg/mL
MIC
PMID28547390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28547390/
RECORD: Rec_0197596 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,6
Bio-Activity Profile
Antimicrobial Antibacterial
Shigella dysenteriae ATCC 9752
50 μg/mL
MIC
PMID28547390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28547390/
RECORD: Rec_0198228 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,6
Bio-Activity Profile
Hemolytic
Human erythrocytes
25-50 μM
Hemolysis
PMID28547390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28547390/
RECORD: Rec_0213878 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
①The X (position: 2 and 6) in sequence are (S)-α-methyl, α-pentenylglycine. Note: the Experimental section presenst that X is (S)-α-methyl, α-pentenylglycine, while the Results section presents that X is pentenylalanine. We incline to the former representation according to previous papers published by the research group which the author belonged
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?id=DRAMP21608
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