‹ ›
MYP_149795
← PREVIOUS NEXT → BACK
Basic Information
Bradykinin-potentiating peptide 10c-6
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Ion channel modulation
Regulatory peptide ▸ Biological modulation
Standard
10 amino acids
C57H80N16O14
Standard
Sequence
QNWPHPQIPP
Physicochemical Analysis
1213.34 Da
6.74
-0.15
-0.41
-0.0153
-1.65
0.10
-0.02
31.39
39.00
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
463.80
-3.07
12.0
15.0
29.0
87.0
7.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0084164 VERIFIED: NO
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Peptide Potentiator
RECORD: Rec_0260037 VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 10c
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Bradykinin-potentiating peptide 10c (Bothrops jararaca): PMID 22869554,15922781 PMID22869554;15922781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22869554/
RECORD: Rec_0280053 VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 10c
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
the cell
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Bradykinin-potentiating peptide 10c (Bothrops jararaca): PMID 19491403,15922781 PMID19491403;15922781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19491403/
RECORD: Rec_0318357 VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 10c
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
angiotensin-converting enzyme
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Bradykinin-potentiating peptide 10c (Bothrops jararaca): PMID 11994001,21185808 PMID11994001;21185808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11994001/
RECORD: Rec_0396605 VERIFIED: YES
Provenance & Taxonomy
Bothrops jararaca [Animal]
Bradykinin-potentiating peptide 10c
8724
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Cardiovascular Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory
B2 receptor
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperThe Bradykinin-potentiating peptides from venom gland and brain of Bothrops jararaca contain highly site specific inhibitors of the somatic angiotensin-converting enzyme PMID15922781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15922781/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2