Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC446H732N128O114S11

DescriptionStandard

        MKFLFLFLVILLAMKPLVSECWMDGKCRLVCKSDEDSVIRCANRKRCCVPSRFLTVRPMTVESMEPWTVPHTSKPVKHRIRPGSRGI
    

Molecular Weight10064.09 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)8.62

Net Charge (pH 7.4) 8.20

Charge Density (pH 7.0) 0.0991

GRAVY Index0.01

Hydrophobic Moment 0.61

Boman Index-0.04

Instability Index45.14

Aliphatic Index 86.09

Aromaticity 0.0690

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3859.29

LogP -30.78

H-bond Donors 144.0

H-bond Acceptors 136.0

Rotatable Bonds 331.0

Heavy Atoms 699.0

Ring Count 17.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374841 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence