Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2405H3799N617O669S14

DescriptionStandard

        MSSSSLSRAWRSRKMLWFLVVLLGVGTEAVTPGIKMKITLKGLDYGKQIGMEFLKFALLQLPIPDFRGSYSVPLVGQVEYAVTGFQVKTIDLGESLVAFAPSSRIKLSMGPAEAQVDGHWSVKVSLIHDSGTFKLSVGDMMLAVLVEVGWDGAGRLVVSPAGCSCLIGHLGITFHGGASWLYNIFTGALEHPLRQEFGNKLCKEIQNAVEALERKLQAIPESSHISSVADLDYSLVAPPLITEQNIELDLKGEFYSRLGHKEAPVPPAPFSLWEQNDCMLLLAFSDFVANSAAFVYYGAGALSWNLTDSTVPKKFPIHINTKIFKGLAPELLKRFPDTPMALQLFARRPPRLQTQPGTLQLLLPGAVQAYVLPNGTSAVPVFLLHVDAEASAQVFISGKNIGASLKLTNVSLTLAHSDVGPFLVDRMETLLYVALKSAILPRINRKLKEGFPLPTLPKTTLQDTAINIQEGFLVIATNVQYGA
    

Molecular Weight52509.53 Da

Isoelectric Point (pI)8.20

Net Charge (pH 7.0)2.38

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0049

GRAVY Index0.22

Hydrophobic Moment 0.78

Boman Index0.18

Instability Index41.26

Aliphatic Index 105.80

Aromaticity 0.0870

Extinction Coeff. Reduced 54890.00

Extinction Coeff. Oxidized 55140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168457 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria