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MYP_149749
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Basic Information
Pleurocidin VA
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C125H184N36O29
Standard
Sequence
GWGSFFKKAAHAGKHAGKAALTHYL
Physicochemical Analysis
2655.02 Da
10.18
4.02
3.65
0.1607
-0.26
0.56
0.15
11.76
55.20
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.32
-8.29
37.0
36.0
85.0
190.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0190130 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
400 μg/mL
IC50
PMID33247193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33247193/
RECORD: Rec_0264367 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
198.2±10.2 μg/mL
IC50
PMID33247193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33247193/
RECORD: Rec_0284791 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID33247193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33247193/
RECORD: Rec_0292899 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Calu-3
250 μg/mL
IC50
PMID33247193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33247193/
RECORD: Rec_0347110 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID33247193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33247193/
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