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MYP_149742
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Basic Information
Neutrophil peptide 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
33 amino acids
C161H283N65O36S6
Standard
Sequence
VVCACRRALCLPRERRAGFCRIRGRIHPLCCRR
Physicochemical Analysis
3897.77 Da
11.40
8.76
8.41
0.2656
-0.11
0.60
-0.37
84.77
85.76
0.0303
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1661.92
-16.93
70.0
52.0
128.0
268.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0304636 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6872705 B2 Evidence URLhttps://patents.google.com/patent/US6872705B2/en PatentUS 6872705 B2
RECORD: Rec_0372529 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral
herpes simplex virus type I
PaperPubMed PMID: 6643497 | PubMed PMID: 3988726 | PubMed PMID: 1311240 PMID6643497;3988726;1311240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6643497/
RECORD: Rec_0396042 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Virus]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
R: 30%; C: 18%
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
C. neofonnans ATCC 52817
0.93 μg/mL
MIC
PaperAntibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages.
RECORD: Rec_0400540 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSelsted M. E., Brown D. M, DeLange R. J., Harwig S. S., Lehrer R. I.. Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J. Biol. Chem., 260, 4579-4584, 1985.
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