Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-4 precursor

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiviral

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC136H229N47O39S6

DescriptionStandard

        ACYCRIGACVSGERLTGACGLNGRIYRLCCR
    

Molecular Weight3338.95 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.1206

GRAVY Index0.30

Hydrophobic Moment 0.65

Boman Index-0.03

Instability Index28.82

Aliphatic Index 81.94

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1407.13

LogP -17.05

H-bond Donors 59.0

H-bond Acceptors 49.0

Rotatable Bonds 109.0

Heavy Atoms 228.0

Ring Count 2.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391928 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide2-30, 4-19, 9-29

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiviral Antifungal

TargetCryptococcus neoformans

Activity10 μg/mL

MethodMIC

FIRST PREV 1 2 3 4

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