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MYP_149720
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Basic Information
Neutrophil antibiotic peptide NP-4 precursor
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
31 amino acids
C136H229N47O39S6
Standard
Sequence
ACYCRIGACVSGERLTGACGLNGRIYRLCCR
Physicochemical Analysis
3338.95 Da
8.96
3.74
3.46
0.1206
0.30
0.65
-0.03
28.82
81.94
0.0645
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1407.13
-17.05
59.0
49.0
109.0
228.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0282282 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0282304 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 502A
50 μg/mL
MIC
PMID2543629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2543629/
RECORD: Rec_0293964 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0318313 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0320052 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperEisenhauer P. B., Harwig S. S., Szklarek D., Ganz T., Selsted M. E., Lehrer R. I.. Purification and antimicrobial properties of three defensins from rat neutrophils. Infect. Immun., 57, 2021-2027, 1989.
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