Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2576H3989N655O736S15

DescriptionStandard

        MRTKQVPVLWACFLLWSLYIASSQTVYPGIKARITQRALDYGLQVGMKVLEQLAKEIVIPDLNGSESLKFLKIDYVKYNFSNIKINAFSFPNTSLAFVPGVGIRALSNHGTANISTNWSVKAPLFRDSGAANLFLSGIYFTGIVAFTRNDFGYPALELQDCHVQVSHARVSFFGSLSALYNSFAEPMEKPILKNLNEMLCPIAISQVEQFNVNISALEVLTKIDNYTVLDCSLISPPEITENHLDFNLKGAFYPLESLVDPPFTPAPFQLPESRDSMLYIGISEYFFKSAAFAHYVSGALGTTLSTREISNYFNQNAQGFGSVLSKIAEIYVLSQPFILQMMATGPPMVNLQRNNFSLEFPAAVIMLTQLDNSTIQPIVSMDFVASTSVGLAILGQKLICSLSLNRFRLSLPENSQRDVKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFINSDIEVLEGYLLVSSDLAHDTSSKPQPNLNSWGDLNLVHRPWREQPTH
    

Molecular Weight56391.15 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-4.72

Net Charge (pH 7.4) -5.57

Charge Density (pH 7.0) -0.0093

GRAVY Index0.12

Hydrophobic Moment 0.71

Boman Index0.16

Instability Index35.83

Aliphatic Index 100.77

Aromaticity 0.1085

Extinction Coeff. Reduced 52830.00

Extinction Coeff. Oxidized 53080.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194113 VERIFIED: NO

Provenance & Taxonomy

OrganismMus caroli (Ryukyu mouse) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria