Peptide Database

Peptide NameNeutrophil defensin 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC155H260N62O45S6

DescriptionStandard

        RRTCRCRFGRCFRRESYSGSCNINGRISSLCCR
    

Molecular Weight3904.50 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)7.70

Net Charge (pH 7.4) 7.41

Charge Density (pH 7.0) 0.2334

GRAVY Index-0.75

Hydrophobic Moment 0.80

Boman Index-0.50

Instability Index74.72

Aliphatic Index 35.45

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1816.71

LogP -26.72

H-bond Donors 77.0

H-bond Acceptors 59.0

Rotatable Bonds 132.0

Heavy Atoms 268.0

Ring Count 3.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380146 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetC. neoformans

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