MYP_149645
Cg-BigDef5
Antimicrobial
Standard
86 amino acids
C451H667N125O120S7
Standard
WAQALLPIWTYTQMTVSAPLFAALVAAYGIYAVTRYGIKKARTRNDSHQCANNRGWCRKSCFGHEYIDWYYTDVCGSFYCCRPRNL
9984.34 Da
9.17
5.87
5.46
0.0683
-0.22
0.59
0.03
18.69
65.93
0.1744
33920.00
34295.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3957.30
-34.94
149.0
135.0
309.0
703.0
24.0
92.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0115583
VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals this sequence is most similar (60%) to Cg-bigdef1 A: 12%. GRAVY: -0.22; M Wt: 9984.49; Mol formula: C451H675N121O120S7; molar extinction coeff: 34495. Chemical modification: the C-terminus is amidated. In addition, three disulfide bonds are formed: C1-C5, C2-C4, and C3-C6
Bio-Activity Profile
Antimicrobial
Bacillus sp. 15.5814
1.25 μM
MIC
RECORD: Rec_0117573
VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals this sequence is most similar (60%) to Cg-bigdef1 A: 12%. GRAVY: -0.22; M Wt: 9984.49; Mol formula: C451H675N121O120S7; molar extinction coeff: 34495. Chemical modification: the C-terminus is amidated. In addition, three disulfide bonds are formed: C1-C5, C2-C4, and C3-C6
Bio-Activity Profile
Antimicrobial
Alteromonas sp. 15.5805
2.5 μM
MIC
RECORD: Rec_0126716
VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals this sequence is most similar (60%) to Cg-bigdef1 A: 12%. GRAVY: -0.22; M Wt: 9984.49; Mol formula: C451H675N121O120S7; molar extinction coeff: 34495. Chemical modification: the C-terminus is amidated. In addition, three disulfide bonds are formed: C1-C5, C2-C4, and C3-C6
Bio-Activity Profile
Antimicrobial
Marinobacterium sp. 05.091-3T1
2.5 μM
MIC
RECORD: Rec_0179346
VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals this sequence is most similar (60%) to Cg-bigdef1 A: 12%. GRAVY: -0.22; M Wt: 9984.49; Mol formula: C451H675N121O120S7; molar extinction coeff: 34495. Chemical modification: the C-terminus is amidated. In addition, three disulfide bonds are formed: C1-C5, C2-C4, and C3-C6
Bio-Activity Profile
Antimicrobial
Pseudoalteromonas sp. 15.5809
>10 μM
MIC
RECORD: Rec_0245116
VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals this sequence is most similar (60%) to Cg-bigdef1 A: 12%. GRAVY: -0.22; M Wt: 9984.49; Mol formula: C451H675N121O120S7; molar extinction coeff: 34495. Chemical modification: the C-terminus is amidated. In addition, three disulfide bonds are formed: C1-C5, C2-C4, and C3-C6
Bio-Activity Profile
Antimicrobial
Ruegeria sp. 15.5815
10 μM
MIC
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