Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC398H658N110O116S7

DescriptionStandard

        MRPKKCFSNVTGFCRKRCKLGETSDKGCLRGKFCCVNQEENKKYKKAPEVPDQPFTQNEKDKVEELVILPTVTLITIIL
    

Molecular Weight9064.60 Da

Isoelectric Point (pI)9.13

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 5.11

Charge Density (pH 7.0) 0.0690

GRAVY Index-0.57

Hydrophobic Moment 0.52

Boman Index-0.17

Instability Index37.79

Aliphatic Index 72.66

Aromaticity 0.0633

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3705.71

LogP -35.42

H-bond Donors 131.0

H-bond Acceptors 129.0

Rotatable Bonds 313.0

Heavy Atoms 631.0

Ring Count 10.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343062 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota monax [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal