Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC277H459N73O77S8

DescriptionStandard

        LTLRILFLAAVGSFLCTDTARSRKCFSTIAGYCKKKCMLGEIYDKPCTKGKLCCISE
    

Molecular Weight6300.57 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)5.69

Net Charge (pH 7.4) 5.37

Charge Density (pH 7.0) 0.0999

GRAVY Index0.29

Hydrophobic Moment 0.42

Boman Index0.05

Instability Index40.20

Aliphatic Index 87.37

Aromaticity 0.0877

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2423.70

LogP -22.05

H-bond Donors 95.0

H-bond Acceptors 91.0

Rotatable Bonds 214.0

Heavy Atoms 435.0

Ring Count 6.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186425 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence