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MYP_149492
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Basic Information
Dynorphin A(1-8)
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
8 amino acids
C46H72N14O10
Standard
Sequence
YGGFLRRI
Physicochemical Analysis
981.15 Da
10.84
1.76
1.55
0.2199
0.00
0.70
-0.03
109.24
97.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
411.05
-2.14
16.0
12.0
31.0
70.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0134334 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Opioid
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID7191256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7191256/
RECORD: Rec_0240939 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Opioid
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID7191256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7191256/
RECORD: Rec_0297406 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Dynorphin A(1-8)
10141
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Dynorphin A(1-8) (Cavia porcellus): PMID 8985124 PMID8985124 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8985124/
RECORD: Rec_0307514 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Dynorphin A(1-8)
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Dynorphin A(1-8) (Sus scrofa): PMID 7191256 PMID7191256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7191256/
RECORD: Rec_0316324 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Opioid
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID7191256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7191256/
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