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MYP_149445
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Basic Information
Hipposin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
51 amino acids
C236H398N86O61
Standard
Sequence
SGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAHRVGAGAPVYL
Physicochemical Analysis
5416.22 Da
12.00
12.63
12.31
0.2476
-0.68
0.83
-0.23
37.04
67.06
0.0588
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2411.19
-30.02
90.0
76.0
183.0
383.0
7.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017617 VERIFIED: YES
Provenance & Taxonomy
Atlantic halibut [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
derived from histone H2A
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
1.3-2.5 μM
MIC
PaperHipposin, a histone-derived antimicrobial peptide in Atlantic halibut (Hippoglossus hippoglossus L.).
RECORD: Rec_0033091 VERIFIED: YES
Provenance & Taxonomy
Hippoglossus hippoglossus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
Gram-
0.3 μM
MIC
PMID12637028 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12637028/
RECORD: Rec_0049989 VERIFIED: NO
Provenance & Taxonomy
Hippoglossus hippoglossus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2020/0308236 A1 Evidence URLhttps://patents.google.com/patent/US20200308236A1/en PatentUS 2020/0308236 A1
RECORD: Rec_0051348 VERIFIED: YES
Provenance & Taxonomy
Atlantic halibut [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
derived from histone H2A
Bio-Activity Profile
Antimicrobial
V. salmonicida
10-20 μM
MIC
PaperHipposin, a histone-derived antimicrobial peptide in Atlantic halibut (Hippoglossus hippoglossus L.).
RECORD: Rec_0059915 VERIFIED: YES
Provenance & Taxonomy
Hippoglossus hippoglossus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
Gram+
0.3 μM
MIC
PMID12637028 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12637028/
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