Peptide Database

Peptide NameSecretogranin-1

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length657 amino acids

Chemical FormulaC3226H5004N1000O1130S7

DescriptionStandard

        APVDNRDHNEEMVTRCIIEVLSNALSKSSVPTITPECRQVLKKSGKEVKGEEKGENQNSKFEVRLLRDPADASGTRWASSREDAGAPVEDSQGQTKVGNEKWTEGGGHSREGVDDQESLRPSNQQASKEAKIYHSEERVGKEREKEEGKIYPMGEHREDAGEEKKHIEDSGEKPNTFSNKRSEASAKKKDESVARADAHSMELEEKTHSREQSSQESGEETRRQEKPQELTDQDQSQEESQEGEEGEEGEEGEEGEEDSASEVTKRRPRHHHGRSGSNKSSYEGHPLSEERRPSPKESKEADVATVRLGEKRSHHLAHYRASEEEPEYGEESRSYRGLQYRGRGSEEDRAPRPRSEESQEREYKRNHPDSELESTANRHGEETEEERSYEGANGRQHRGRGREPGAHSALDTREEKRLLDEGHYPVRESPIDTAKRYPQSKWQEQEKNYLNYGEEGDQGRWWQQEEQLGPEESREEVRFPDRQYEPYPITEKRKRLGALFNPYFDPLQWKNSDFEKRGNPDDSFLEDEGEDRNGVTLTEKNSFPEYNYDWWERRPFSEDVNWGYEKRSFARAPQLDLKRQYDGVAELDQLLHYRKKADEFPDFYDSEEQMGPHQEANDEKARADQRVLTAEEKKELENLAAMDLELQKIAEKFSQRG
    

Molecular Weight76100.73 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-46.09

Net Charge (pH 7.4) -47.70

Charge Density (pH 7.0) -0.0702

GRAVY Index-1.65

Hydrophobic Moment 0.67

Boman Index-0.40

Instability Index72.34

Aliphatic Index 39.98

Aromaticity 0.0670

Extinction Coeff. Reduced 82280.00

Extinction Coeff. Oxidized 82405.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153870 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyChromogranin/secretogranin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer79 Phosphoserine; Ser80 Phosphoserine; Ser127 Phosphoserine; Tyr151 Sulfotyrosine; Ser236 Phosphoserine; Ser240 Phosphoserine; Ser280 Phosphoserine; Ser281 Phosphoserine; Ser298 Phosphoserine; Ser322 Phosphoserine; Tyr328 Sulfotyrosine; Ser355 Phosphoserine; Ser358 Phosphoserine; Tyr449 Sulfotyrosine; Tyr452 Sulfotyrosine; Ser512 Phosphoserine; Ser523 Phosphoserine; Tyr546 Sulfotyrosine; Tyr548 Sulfotyrosine; Tyr604 Sulfotyrosine; Ser606 Phosphoserine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor