Peptide Database

Peptide NameAlglucosidase alfa

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1276H1961N343O373S12

DescriptionStandard

        AHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQP
    

Molecular Weight28459.07 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-3.62

Net Charge (pH 7.4) -4.30

Charge Density (pH 7.0) -0.0142

GRAVY Index-0.26

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index47.81

Aliphatic Index 76.90

Aromaticity 0.0980

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30285.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321663 VERIFIED: YES

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyEnzyme

Tax ID10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-Life2.3 ± 0.4 h.