Peptide Database

Peptide NameSLAY-screened peptide P2159

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC56H97N23O19

DescriptionStandard

        ESRARSTHTVPR
    

Molecular Weight1396.51 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)1.92

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.1603

GRAVY Index-1.57

Hydrophobic Moment 0.34

Boman Index-0.61

Instability Index81.37

Aliphatic Index 32.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 707.23

LogP -10.72

H-bond Donors 27.0

H-bond Acceptors 22.0

Rotatable Bonds 44.0

Heavy Atoms 98.0

Ring Count 2.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369935 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/