Peptide Database

Peptide NameE1P49

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC109H160N24O23

DescriptionStandard

        WKVPFDFWRGVISLTPLL
    

Molecular Weight2174.58 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0422

GRAVY Index0.62

Hydrophobic Moment 0.61

Boman Index0.35

Instability Index24.08

Aliphatic Index 118.89

Aromaticity 0.2222

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 737.70

LogP -0.05

H-bond Donors 26.0

H-bond Acceptors 24.0

Rotatable Bonds 63.0

Heavy Atoms 156.0

Ring Count 8.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0070490 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetHIV-1 NL4-3; TZM-bl cells

Activity17.3±3.2 μM

MethodVirus-infection inhibition IC50 assay