Peptide Database

Peptide NameL5K5W9 (L5K5Wn model peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC71H127N17O12

DescriptionStandard

        KLLKKLLKWLK
    

Molecular Weight1410.87 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.4323

GRAVY Index-0.13

Hydrophobic Moment 0.84

Boman Index-0.13

Instability Index-18.28

Aliphatic Index 177.27

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 500.21

LogP 1.85

H-bond Donors 18.0

H-bond Acceptors 17.0

Rotatable Bonds 53.0

Heavy Atoms 100.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102790 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMRSA-TK784

Activity8 μg/mL

MethodMIC

RECORD: Rec_0132142 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae ATCC 10031

Activity2 μg/mL

MethodMIC

RECORD: Rec_0132816 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 6538p

Activity2 μg/mL

MethodMIC

RECORD: Rec_0139122 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 63.6%, E 0.0%, T 18.2%, C 18.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Toxic Antimicrobial Hemolytic

RECORD: Rec_0154970 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

TargetBacillus subtilis ATCC 6633 (MIC = 2microg/ml), Staphylococcus aureus ATCC 6538p (MIC = 2microg/ml), Staphylococcus epidermis ATCC 12228 (MIC = 2microg/ml), Micrococcus luteus ATCC 10240 (MIC = 4microg/ml), MRSA-TK784 (MIC = 8microg/ml), Escherichia coli ATCC 25922 (MIC = 2microg/ml), Shigella dysenteriae ATCC 9752 (MIC = 2microg/ml), Salmonella typhimurium ATCC 14028 (MIC = 2microg/ml), Klebsiella pneumoniae ATCC 10031 (MIC = 2microg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC = 4microg/ml)

Activity64 μg/mL

MethodMHC

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