MYP_149336
Dosotamide A
Antimicrobial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Standard
6 amino acids
C35H54N8O8
Standard
WLLING
714.85 Da
5.53
-0.24
-0.44
-0.0400
1.22
0.16
0.67
3.85
195.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
267.70
0.19
9.0
8.0
21.0
51.0
2.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0023619
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0038660
VERIFIED: YES
Provenance & Taxonomy
Streptomyces nov [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
APD analysis reveals that the sequence of Dosotamide A shows 35.7% similarity to insect Pd_mastoparan PDD-B. Active against B. subtilis. The third position is a D-amino acid. I4 is an L-allo-Ile
Bio-Activity Profile
Antimicrobial
Bacillus subtilis. The third position is a D-amino acid. I4 is an L-allo-Ile
RECORD: Rec_0424302
VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial