MYP_149304
Hl Defensin-1, HlDFS1
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antibacterial
▸
Anti-Mycobacterium
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
37 amino acids
C177H294N72O43S6
Standard
GFGCPFNARRCHRHCRSIRRRAGYCAGRLRLTCTCVR
4311.07 Da
11.41
9.87
9.48
0.2669
-0.52
0.84
-0.39
102.16
47.57
0.0811
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1902.50
-24.06
80.0
61.0
140.0
298.0
6.0
37.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0316043
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Human myelogenous leukemia K562
RECORD: Rec_0318267
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Candida albicans CAU 0037
50 μM
MIC50
RECORD: Rec_0327233
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
A549 (Not active up to 20 μM)
RECORD: Rec_0343930
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
Human erythrocytes
<5 %
Hemolysis
RECORD: Rec_0347346
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
10 μM
Hemolysis
Showing 5 records on this page · Page 7 of 9