Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2637H4129N797O809S20

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSTLPNCTEHGRGVIRVGDKTTACPKCGKQGVVADGEPRVNWMGQTSAVDGSVVICGCPHGTNRVIAPSGEWLGSGPSPEQIAQEKHQAMLAARRKEQEAEAQRQAEERDRNRVFAKSCLRGEGCNDAGTGSEPHTNFAEMAFYQAIPNNALQHAQAAKRKVLPKPKQRSALYLWWNGHHEEMDYQAAVAAEERAWTARNAIADASELALVSGRTITSGTWAVRGAALGEIATGGLGAPVAGLLIGMYPGKLNDGEQDFIDRMRAEQMREAPTRVRFTWQNDASGNPTPRGWHTPPGKDSVRVRRMEWDSQRQAYTFTTEEDPGITLIWTPDRTGDSKPWDTGNHNPVRIPNPVVVDPLPEDTGIGATTSPTPEEKTFADYILILPVGGVPPIYVYIRHNPGQVTGKGQKISGIWLSDANTGNGSPIPSQIADRLRGQTFTDFDQFRKAFWLEVSRDPVLLEQFISNNRASMRKGNAPYTRTPDSVGKRERYEIHHIQPISQGGKVYDVDNMGITTPKHHIKIHKGE
    

Molecular Weight60582.15 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)3.90

Net Charge (pH 7.4) 2.61

Charge Density (pH 7.0) 0.0071

GRAVY Index-0.66

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index34.00

Aliphatic Index 64.20

Aromaticity 0.0688

Extinction Coeff. Reduced 90870.00

Extinction Coeff. Oxidized 91370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386629 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin/Colicin

Tax ID550

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli