Peptide Database

Peptide NameSyn-larvacin-19

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC140H229N41O33

DescriptionStandard

        AGKEWIFQRLKKKIQEKGKRATIAW
    

Molecular Weight3014.57 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.2318

GRAVY Index-0.97

Hydrophobic Moment 0.71

Boman Index-0.26

Instability Index7.35

Aliphatic Index 74.40

Aromaticity 0.1200

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1254.23

LogP -7.83

H-bond Donors 45.0

H-bond Acceptors 39.0

Rotatable Bonds 108.0

Heavy Atoms 214.0

Ring Count 5.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139903 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50

RECORD: Rec_0208150 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity0.73 μM

MethodIC50