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MYP_149284
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Basic Information
Thurincin H
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
1 amino acids
C4H7NO4
Standard
Sequence
D
Physicochemical Analysis
133.10 Da
4.30
-1.24
-1.44
-1.2356
-3.50
0.90
-0.90
0.00
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
100.62
-1.13
3.0
3.0
3.0
9.0
0.0
0.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002217 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0254076 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Amino acid
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Umami
PaperTastes produced by peptides containing ionic groups and by related compounds. Biosci., Biotech., Biochem., 60, 1637-1642, 1996
RECORD: Rec_0259154 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
tert-Butyloxycarbonyl
Fluoromethyl ketone
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium falciparum Itg2
>100 μM
LD50; Microscopy (Giemsa staining)
PMID1939639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1939639/
RECORD: Rec_0408690 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Amino acid
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Sour
PaperTastes produced by peptides containing ionic groups and by related compounds. Biosci., Biotech., Biochem., 60, 1637-1642, 1996
RECORD: Rec_0418542 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Amino acid
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Salty
PaperTastes produced by peptides containing ionic groups and by related compounds. Biosci., Biotech., Biochem., 60, 1637-1642, 1996