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MYP_149254
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Basic Information
Phylloseptin-H11
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C99H151N27O22
Standard
Sequence
FLSLIPHAINAVGVHAKHF
Physicochemical Analysis
2071.43 Da
8.77
1.02
0.66
0.0537
0.85
0.46
0.43
-1.97
128.42
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
753.71
-3.80
25.0
26.0
63.0
148.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035334 VERIFIED: YES
Provenance & Taxonomy
Pithecopus hypochondrialis [Animal]
317381
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
PaperA combined mass spectrometric and cDNA sequencing approach to the isolation and characterization of novel antimicrobial peptides from the skin secretions of Phyllomedusa hypochondrialis azurea.
RECORD: Rec_0040834 VERIFIED: YES
Provenance & Taxonomy
Northern orange-legged [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID17553595 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17553595/
RECORD: Rec_0186366 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa azurea [Animal]
Phylloseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 17553595 PMID17553595 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17553595/
RECORD: Rec_0199155 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0210628 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
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