Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC926H1462N256O246S9

DescriptionStandard

        PTVLPAAHEPMLLLAITEFVANSAAFAYFTAGALRRNISSNTLPRRFPLQLRTKSMGVFSPQLQERYPDQPMELHLSARRQPLLSCHPDALHGALFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTPCLRGGPLCLPHAGLMGLPVPQVKRLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight20405.67 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 5.99

Charge Density (pH 7.0) 0.0343

GRAVY Index0.12

Hydrophobic Moment 0.57

Boman Index0.14

Instability Index62.41

Aliphatic Index 95.53

Aromaticity 0.0745

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7798.53

LogP -89.65

H-bond Donors 268.0

H-bond Acceptors 267.0

Rotatable Bonds 634.0

Heavy Atoms 1437.0

Ring Count 44.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244476 VERIFIED: NO

Provenance & Taxonomy

OrganismSpheniscus mendiculus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence