Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC392H599N105O108S7

DescriptionStandard

        PFHSVILYFHDSGPIDLNNFFFCTVRSGFEDKVCGHGTALCRVKCLPNEIKIGKCPNAFPCCLKTFENHSLNTLKVNS
    

Molecular Weight8735.04 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)2.24

Net Charge (pH 7.4) 1.86

Charge Density (pH 7.0) 0.0288

GRAVY Index0.00

Hydrophobic Moment 0.50

Boman Index0.09

Instability Index30.48

Aliphatic Index 76.15

Aromaticity 0.1154

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3377.24

LogP -32.65

H-bond Donors 121.0

H-bond Acceptors 121.0

Rotatable Bonds 281.0

Heavy Atoms 612.0

Ring Count 18.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067053 VERIFIED: NO

Provenance & Taxonomy

OrganismSarcophilus harrisii [Animal]

FamilyDefensin

Tax ID9305

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal