Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC194H324N62O57S

DescriptionStandard

        HATCSLAFALATSVALATRNDLLLRWAAARDAQTILSKRDR
    

Molecular Weight4469.09 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0693

GRAVY Index0.13

Hydrophobic Moment 0.59

Boman Index-0.03

Instability Index38.58

Aliphatic Index 107.56

Aromaticity 0.0488

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1947.00

LogP -21.61

H-bond Donors 73.0

H-bond Acceptors 62.0

Rotatable Bonds 147.0

Heavy Atoms 314.0

Ring Count 4.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020216 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 87.8%, E 0.0%, T 7.3%, C 4.9% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0319991 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyHeptad repeat peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsScrambled sequence control

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); Vero

MethodPlaque assay

PaperAnalysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and B. | Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M. | J Gen Virol. 2006 | PMID:16603508 PMID16603508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16603508/