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MYP_149180
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Basic Information
Cecropin A-like 4 (3-18)[K2W;G5,12W;K6W;E9W;Q13K;H14N;T15W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C123H170N32O18
Standard
Sequence
LWKIWWKIWRVWKNWR
Physicochemical Analysis
2384.87 Da
12.00
4.76
4.55
0.2973
-0.79
0.77
-0.04
7.08
91.25
0.3750
33000.00
33000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.51
3.60
33.0
23.0
72.0
173.0
12.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus MW2
13.42 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0043374 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human hepatocellular carcinoma HepG2
20-30 % Killing
Killing
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0149538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella aerogenes ATCC 13048
53.67 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0189810 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PA14
13.42 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0197210 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 10231
26.84 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
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