Peptide Database

Peptide NameEndolysin B (Gene 12 protein) (Gp12) (Mycolylarabinogalactan esterase) (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length254 amino acids

Chemical FormulaC1304H1993N349O358S7

DescriptionStandard

        MSKPWLFTVHGTGQPDPLGPGLPADTARDVLDIYRWQPIGNYPAAAFPMWPSVEKGVAELILQIELKLDADPYADFAMAGYSQGAIVVGQVLKHHILPPTGRLHRFLHRLKKVIFWGNPMRQKGFAHSDEWIHPVAAPDTLGILEDRLENLEQYGFEVRDYAHDGDMYASIKEDDLHEYEVAIGRIVMKASGFIGGRDSVVAQLIELGQRPITEGIALAGAIIDALTFFARSRMGDKWPHLYNRYPAVEFLRQI
    

Molecular Weight28511.35 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-6.59

Net Charge (pH 7.4) -7.38

Charge Density (pH 7.0) -0.0259

GRAVY Index-0.15

Hydrophobic Moment 0.87

Boman Index0.10

Instability Index32.47

Aliphatic Index 92.99

Aromaticity 0.1063

Extinction Coeff. Reduced 47900.00

Extinction Coeff. Oxidized 47900.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126592 VERIFIED: YES

Provenance & Taxonomy

OrganismMycobacterium phage D29 [Virus]

FamilyL5likevirus endolysin B protein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic