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MYP_149147
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Basic Information
L15
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
18 amino acids
C101H170N38O19S
Standard
Sequence
PAWRKARRWARRMKKLAA
Physicochemical Analysis
2252.74 Da
12.00
7.96
7.89
0.4420
-1.27
1.02
-0.59
102.54
49.44
0.1111
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
963.17
-6.89
39.0
28.0
76.0
159.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193561 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxicity tested Low toxicity
Normal fibroblasts
>444 μM
Cytotoxicity IC50 assay
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides. PMID:12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0231556 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-29; Meth A; MT-1 tumor cells
Cytotoxicity IC50 assay
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides. PMID:12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0300488 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Hemolysis tested Low hemolysis
Human erythrocytes
>444 μM
Hemolysis EC50 assay
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides. PMID:12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0316960 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
Meth A mouse fibrosarcoma cells
87 μM
Cytotoxicity IC50 assay
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides. PMID:12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0318343 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; synthetic construct [Synthetic]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
HT-29; Meth A; MT-1 tumor cells
Cytotoxicity IC50 assay
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides. PMID:12366526 PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
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