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MYP_149062
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Basic Information
P8
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
12 amino acids
C56H95N15O17S2
Standard
Sequence
CDVIALLCHLNT
Physicochemical Analysis
1314.57 Da
5.08
-1.17
-1.45
-0.0976
1.33
0.26
0.39
45.31
162.50
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
512.72
-3.85
19.0
19.0
41.0
90.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023066 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
west nile virus(WNV):inhibition of virus infection in Vero cells(P10 significantly inhibited WNV infectivity)
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0044653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-WNV Entry inhibition
West nile virus(WNV) | Vero cells
Mammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h
PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 Feb;81(4):2047-55. | DOI:10.1128/JVI.01840-06 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0303713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0325757 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0402392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
West Nile virus (Virus entry); Vero
qPCR
PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/